| Item Type | Name |
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Concept
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Ubiquitin-Protein Ligases
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Concept
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Oxidative Stress
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Concept
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Organ Size
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Concept
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Superoxide Dismutase
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Concept
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Reactive Oxygen Species
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Concept
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Glycogen Synthase
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Concept
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Uridine Diphosphate N-Acetylglucosamine
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Concept
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Glycogen Synthase Kinase 3
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Concept
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SKP Cullin F-Box Protein Ligases
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Concept
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Endosomal Sorting Complexes Required for Transport
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Concept
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Mass Screening
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Concept
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Database Management Systems
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Concept
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Stress, Physiological
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Concept
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Cohort Studies
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Concept
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Renin-Angiotensin System
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Concept
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Muscle Strength
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Concept
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Research Support as Topic
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Concept
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Protein-Serine-Threonine Kinases
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Concept
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Dietary Supplements
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Concept
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Up-Regulation
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Utah
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Concept
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Retrospective Studies
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Concept
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Insulin-Secreting Cells
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Concept
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Signal Transduction
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Concept
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Nitric Oxide Synthase Type III
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Concept
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Gene Expression Profiling
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Concept
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Tandem Mass Spectrometry
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Concept
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Diet, Sodium-Restricted
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Concept
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RNA, Small Interfering
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Concept
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Genetic Association Studies
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Concept
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Genes, Tumor Suppressor
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Concept
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Insulin Receptor Substrate Proteins
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Concept
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Streptozocin
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Sensitivity and Specificity
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Concept
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Selection, Genetic
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Concept
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Ultrasonography, Interventional
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Concept
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National Institutes of Health (U.S.)
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Concept
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Extracellular Signal-Regulated MAP Kinases
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Concept
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Cross-Sectional Studies
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Concept
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Sarcopenia
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Concept
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Succinate Dehydrogenase
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Concept
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Thiobarbituric Acid Reactive Substances
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Concept
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Genome-Wide Association Study
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Concept
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Cardiovascular System
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Concept
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United States
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Concept
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Sodium Chloride, Dietary
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Concept
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United States Food and Drug Administration
|
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Concept
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Von Hippel-Lindau Tumor Suppressor Protein
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Concept
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Anemia, Sickle Cell
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Concept
|
Alleles
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|
Concept
|
Muscle, Skeletal
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Concept
|
Mice, Mutant Strains
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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|
Academic Article
|
Utility of ultrasound-guided fine-needle aspiration of parathyroid adenomas for localization before minimally invasive parathyroidectomy.
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Academic Article
|
PAS kinase is required for normal cellular energy balance.
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|
Academic Article
|
A role for the transcriptional coactivator PGC-1alpha in muscle refueling.
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|
Academic Article
|
Metabolic insight into mechanisms of high-altitude adaptation in Tibetans.
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|
Academic Article
|
Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS).
|
|
Academic Article
|
Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity.
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|
Academic Article
|
Increased glucose disposal and AMP-dependent kinase signaling in a mouse model of hemochromatosis.
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|
Academic Article
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Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase.
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Academic Article
|
Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells.
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|
Academic Article
|
Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.
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Academic Article
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Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus.
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|
Academic Article
|
Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
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|
Academic Article
|
Systemic PPAR? deletion impairs circadian rhythms of behavior and metabolism.
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Academic Article
|
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.
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|
Academic Article
|
Adipocyte iron regulates adiponectin and insulin sensitivity.
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|
Academic Article
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Hyperglycemia and inhibition of glycogen synthase in streptozotocin-treated mice: role of O-linked N-acetylglucosamine.
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|
Academic Article
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Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
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|
Academic Article
|
Introduction to a mini-forum on "glyconutrients".
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|
Academic Article
|
Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
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|
Academic Article
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Regulation of Akt signaling by O-GlcNAc in euglycemia.
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Academic Article
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Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis.
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Academic Article
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Proposed regulation of gene expression by glucose in rodent heart.
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Academic Article
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Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.
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|
Academic Article
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Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion.
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|
Academic Article
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Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesis.
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|
Academic Article
|
Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux.
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Academic Article
|
Bridging the gap between basic and clinical investigation.
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|
Academic Article
|
Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid.
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Academic Article
|
Iron and diabetes risk.
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|
Academic Article
|
Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice.
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|
Academic Article
|
The 3T3-L1 adipocyte glycogen proteome.
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|
Academic Article
|
Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse.
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|
Academic Article
|
The role of mPer2 clock gene in glucocorticoid and feeding rhythms.
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|
Academic Article
|
Increased strength and physical performance with eccentric training in women with impaired glucose tolerance: a pilot study.
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Academic Article
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Analysis of hepatic glycogen-associated proteins.
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|
Academic Article
|
Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.
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|
Academic Article
|
Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1a.
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|
Academic Article
|
Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
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|
Academic Article
|
The Utah Center for Clinical and Translational Science: transformation through collaboration.
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Academic Article
|
Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.
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Academic Article
|
Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells.
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|
Academic Article
|
Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis.
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|
Academic Article
|
Muscle damage and muscle remodeling: no pain, no gain?
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|
Academic Article
|
Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison.
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|
Academic Article
|
Diabetes and hemochromatosis.
|
|
Academic Article
|
Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic ß-cell function and vascularization.
|
|
Academic Article
|
Anti-obesity and pro-diabetic effects of hemochromatosis.
|
|
Academic Article
|
Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans.
|
|
Academic Article
|
Hexosamines as mediators of nutrient sensing and regulation in diabetes.
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|
Academic Article
|
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.
|
|
Academic Article
|
A genetic mechanism for Tibetan high-altitude adaptation.
|
|
Academic Article
|
Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes.
|
|
Academic Article
|
Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.
|
|
Academic Article
|
Dietary iron controls circadian hepatic glucose metabolism through heme synthesis.
|
|
Academic Article
|
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia.
|
|
Academic Article
|
Genetic determinants of Tibetan high-altitude adaptation.
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|
Academic Article
|
Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.
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|
Academic Article
|
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
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|
Academic Article
|
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.
|
|
Academic Article
|
Adipocyte iron regulates leptin and food intake.
|
|
Academic Article
|
Metabolic aspects of high-altitude adaptation in Tibetans.
|
|
Academic Article
|
Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver.
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|
Grant
|
University of Utah Clinical Research Curriculum Award
|
|
Grant
|
Iron reduction by phlebotomy for the prevention and treatment of type 2 diabetes
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-UL1
|
|
Grant
|
Iron And Metabolism: Altered Fuel Oxidation And Mitochondrial Dysfunction
|
|
Grant
|
Wake Forest Clinical and Translational Science Award
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-TL1
|
|
Grant
|
University of Utah Center for Clinical and Translational Science
|
|
Grant
|
University of Utah Center for clinical and Translational Science
|
|
Grant
|
Hexosamines, Glucose Toxicity and Insulin Resistance
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-UL1
|
|
Grant
|
ANIMAL MODELS OF DIABETIC CARDIOVASCULAR COMPLICATIONS
|
|
Grant
|
Interdisciplinary Training Program in Metabolism
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-KL2
|
|
Grant
|
University of Utah Center for clinical and Translational Science
|
|
Grant
|
DIABETES IN HEMOCHROMATOSIS: PREVALENCE AND MECHANISMS
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-KL2
|
|
Grant
|
University of Utah Center for Clinical and Translational Science-TL1
|
|
Grant
|
Wake Forest Short-term Research Training Program
|
|
Grant
|
ALTERNATE FORMS OF THE INSULIN RECEPTOR
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|
Grant
|
Iron, the circadian clock, and diabetes risk
|
|
Grant
|
Diabetes in Hemochromatosis: Prevalence and Mechanisms
|
|
Academic Article
|
Adipose Tissue Transferrin and Insulin Resistance.
|
|
Academic Article
|
Hyperglycemia during first-line R-CHOP or dose adjusted R-EPOCH chemotherapy for non-Hodgkin lymphoma is prevalent and associated with chemotherapy alteration - a retrospective study.
|
|
Academic Article
|
Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces.
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|
Grant
|
Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease
|
|
Academic Article
|
Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance.
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|
Academic Article
|
Iron down-regulates leptin by suppressing protein O-GlcNAc modification in adipocytes, resulting in decreased levels of O-glycosylated CREB.
|
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Academic Article
|
Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.
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Grant
|
North Carolina Diabetes Research Center
|
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Grant
|
Mechanism of Integrative Metabolic Regulation by Iron and Hypoxia
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